For an oocyte to get Completely ready for fertilization and progress into an embryo, the appropriate list of genes has to be turned on. Namekawa suspected this pre-programming with the oocyte genome comes about in various levels — the primary a single starting up throughout the time a female is born. He thought that chromatin remodeling proteins did much of the function, by shifting spools about.
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This protein may “build and keep the chromatin point out,” states Namekawa — holding the spools in position as well as the oocytes genetically primed as the mouse matures.
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